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Final candidate Z-MAB®s exhibit excellent CMC and pharmacokinetic properties
Most of the biological activity of TNF is mediated by TNFR1
CD269 Tag: Aglycosylated mouse IgG2a-Fc GenBank accession: NM_001192 SwissPro accession: Q02223 Construction: h
Bertrand MJM
Human TNFR1 Mouse IgG2a Aglycosylated Fc protein-tag_His-Flag-Myc Final candidate Z-MAB®s exhibit excellentTNFR1, a type I membrane protein, is a prototype of the TNF receptor superfamily. TNF binds with high affinity to two members of the TNFR superfamily, TNFR1 (P55) which is activated by both membrane anchored TNF (tmTNF) and soluble TNF, and TNFR2 (P75) which is activated mainly by tmTNF. Interacting protein(s): TNF (P7113T), TNF (P7113F), TNF (P7113M), LT a (P7006M) Related products: TNF Receptor Superfamily Read all details below including Quick
