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One of them is that targeted land destruction can definitely work to take out problematic lands, but they wont truly set your opponents back

There is some interesting synergy to be had here, as if you have three poison on your opponent, you probably have some Toxic creatures in play, in which case tapping down a blocker is going to be increasingly problematic for your opponent

Assembly -5: 5 black Digimon cards w/[Maquinamon] in text Lower Text [All Turns] [Once Per Turn] When effects add to this Digimon's digivolution cards, delete 1 of your opponent's Digimon with the lowest play cost

Whatever spell you pick costs three more mana to cast, which is a huge tax effect to be subjected to and is capable of setting your opponents back several turns