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Mal-Propionyl-Dap(m-PEG4)-Val-Ala-OH ptotac ligand 77 SMILES: [O-]S(=O)(=O)C1=CC(=CC=C1C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)S(=O)(=O)NCC#C Purity (HPLC):

SKU: 87598567480

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Description

77 SMILES: [O-]S(=O)(=O)C1=CC(=CC=C1C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)S(=O)(=O)NCC#C Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

Product Name Mal-Propionyl-PEG8-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Synonyms CAS Number Related CAS Molecular Formula C98H153N13O30 Molecular Weight 1993

thus all the instrument settings of the ROX conjugates would be applicable to the applications of ROX alkyne conjugates

such as the copper-catalyzed azide-alkyne cycloaddition (CuAAC) and the strain-promoted alkyne-azide cycloaddition (SPAAC)

Mal-Propionyl-Dap(m-PEG4)-Val-Ala-OH ptotac ligand 77 SMILES: [O-]S(=O)(=O)C1=CC(=CC=C1C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)S(=O)(=O)NCC#C Purity (HPLC):SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine

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