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DBCO-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-PNP Size:100mg Mayor-Ruiz

SKU: 57591983247

4.1
USD445.00 USD488.00

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Description

Mayor-Ruiz

NCCCCC1=CC=C2C(=O)N(CC2=C1)C1CCC(=O)NC1=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Although tetramethylrhodamine (TMR) maleimides and iodoacetamides are popular thiol-reactive labeling reagents

275 (2024) paper studing DCAF1-based PROTACs

DBCO-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-PNP Size:100mg Mayor-RuizSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further

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