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DBCO-Hexanoyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP halide allowing the non-internalized probe to

SKU: 43336238321

4.3
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Description

allowing the non-internalized probe to be released from the cell surface using the reducing agent sodium 2-mercaptoethanesulfonate (MESNA)

Product Name Thalidomide-5'-O-PEG2-C2-azide Synonyms CAS Number 2640388-57-2 Related CAS Molecular Formula C19H21N5O7 Molecular Weight 431

Product Name Phthalimidinoglutarimide-5'-C3-O-PEG1-OH Synonyms CAS Number n/a Related CAS Molecular Formula C18H22N2O5 Molecular Weight 346

161 Purity (HPLC) >= 95% Solubility DMSO

DBCO-Hexanoyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP halide allowing the non-internalized probe toSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG,

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