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Product Name Lenalidomide-C2-acid Synonyms Lenalidomide-4'-C2-acid CAS Number 2338824-28-3 Related CAS Molecular Formula C16H17N3O5 Molecular Weight 331
The payload is monomethyl auristatin E (MMAE)
Hormone Receptor-Positive
Bioconjugate Chemistry
Mal-Propionyl-PEG6-Val-Cit-PAB(m-PEG4)-Exatecan Size:10mg Product Name Lenalidomide-C2-acid Synonyms Lenalidomide-4'-C2-acidSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I
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